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Updated: May 22, 2025

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
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Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics

Published on: June 17, 2022

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设计一个级联的同热信号放大网络,使用二次-二重组的原始发光器,用于无标签检测终端脱氧核酸转移酶活性

Jia Zhao1, Zhuqi Sui2, Haiyan Dong3

  • 1Jiaxing Key Laboratory of Molecular Recognition and Sensing, College of Biological and Chemical Engineering, Jiaxing University, Jiaxing, 314001, China; Fujian Key Laboratory of Translational Research in Cancer and Neurodegenerative Diseases, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China.

Talanta
|March 14, 2025
PubMed
概括

这项研究引入了一种新的,无标签的方法来检测终端脱氧核样转移酶 (TdT) 活性,这是一个关键的白血病生物标志物. 这种高效的测定方法提供了高灵敏度和特异性,以改善分子诊断.

关键词:
级联同热放大级别的同热放大.模态 - 帕林德罗姆原始体 (Di-PP) 的初始体.光信号放大放大 光信号放大没有标签的检测检测.终端脱氧核样转移酶 (TdT) 的使用

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