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Updated: May 22, 2025

Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors
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Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors

Published on: May 1, 2019

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繁殖史和转录因子水平驱动直接转化到运动神经元

Nathan B Wang1, Brittany A Lende-Dorn1, Adam M Beitz1

  • 1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Cell systems
|March 14, 2025
PubMed
概括

我们开发了一种高效的系统,将纤维细胞转化为运动神经元. 细胞增殖史和转录因子水平共同推动这种细胞身份转换.

关键词:
细胞状态 细胞状态细胞酸盐过渡细胞酸盐过渡直接转换的直接转换分子系统生物学分子生物学运动神经元 运动神经元它们的扩散和扩散.重编程是重新编程.合成生物学 合成生物学转录因子的转录因子

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