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Updated: May 22, 2025

Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics
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Monitoring the Cancer-Immunity Cycle and Exploring Tumor Microenvironment Dynamics

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显著的CD8+ T细胞动态与对新辅助癌症免疫疗法的反应有关

Housaiyin Li1, Dan P Zandberg2, Aditi Kulkarni3

  • 1UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Molecular Genetics and Development Biology Graduate Program, University of Pittsburgh, Pittsburgh, PA, USA.

Cancer cell
|March 14, 2025
PubMed
概括

针对头癌的PD-1与LAG-3或CTLA-4的双重免疫疗法显示出不同的免疫细胞动态. 反PD-1+LAG-3重新编程耗尽的T细胞,而反PD-1+CTLA-4扩展现有的T细胞.

关键词:
在 CTLA-4 中.头癌是头部和部的癌症.现场行动组-3在PD-1中使用PD-1.T细胞动态 T细胞动态临床试验临床试验临床试验临床试验临床试验组合免疫疗法组合免疫疗法多光谱成像技术的使用.单细胞基因组学 单细胞基因组学瘤免疫学 瘤免疫学

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