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一种免疫肝脏微生理系统方法,用于评估和质量控制由Polygonum multiflorum thunb.诱导的肝毒性. 提取物 提取物

Quanfeng Deng1, Yueyang Qu2, Yong Luo3

  • 1Jiangsu Key Laboratory of Neuropsychiatric Disease and College of Pharmaceutical Science, Suzhou Medical College, Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases, Soochow University, 215127, Suzhou, Jiangsu Province, China; Intensive Care Unit, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518031, China.

Journal of ethnopharmacology
|March 14, 2025
PubMed
概括

一个新的微生理系统,i-LOC,有效地评估了Polygonum multiflorum Thunb. (PMT) 肝毒性通过模拟免疫-肝脏相互作用. 这种先进的方法为动物试验提供了一种敏感,具有成本效益的替代方案,以确保草药的安全性.

关键词:
生物毒性评价生物毒性评价奇异的同步性肝毒性免疫 - 肝脏芯片天生的免疫系统天生的免疫系统.在芯片上的肝脏.器官在芯片上的器官

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