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通过使用Gd-EOB-DTPA的肝磁共振成像来评估肝胆相位图像的评估方法的表征

Yasuo Takatsu¹, Shohei Harada², Yuya Yamatani³

¹Graduate School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan; Department of Molecular Imaging, Clinical Collaboration Unit, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan; Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan.

Magnetic resonance imaging

|March 14, 2025

概括

量化肝对比度 (Q-LSC) 和肝细胞吸收指数 (HUI) 评估了加多-乙氧-二乙烯胺五酸 (Gd-EOB-DTPA) 增强的肝脏MRI. 虽然Q-LSC显示一致性,但HUI随着肝体积的变化而变化,这表明Q-LSC对于肝胆阶段评估更简单.

科学领域:

放射学和成像学放射学和成像学
肝胆系统成像肝胆系统成像
医学物理医学物理

背景情况:

使用加多-乙氧基-二甲基胺五酸 (Gd-EOB-DTPA) 的肝胆相 (HBP) 成像对于肝脏评估至关重要.
需要定量指标来标准化HBP图像评估.
肝对比度 (Q-LSC) 和肝细胞吸收指数 (HUI) 是潜在的定量措施.

研究的目的:

为了表征定量肝对比度 (Q-LSC) 和肝细胞吸收指数 (HUI) 以评估肝胆相 (HBP) 图像.
为了比较基于ROI (R-LSC,R-HUI) 和基于体积 (V-LSC,V-HUI) 的测量方法.
在肝脏MRI中确定从Q-LSC和HUI获得的结果的差异.

主要方法:

29名患者接受了用Gd-EOB-DTPA的3.0 T MRI.
信号强度 (SI) 测量了肝脏副细胞和脏的定义感兴趣区域 (ROI).
计算了Q-LSC和HUI,以及整个肝脏和细分肝脏的ROI和体积值.

主要成果:

基于ROI (R-LSC) 和基于体积 (V-LSC) 的量化肝对比值显示,肝脏部分之间没有显著差异.
肝细胞吸收指数 (HUI) 值,除了R-HUI和V-HUI之间的值,在整个肝脏中显示出显著差异 (P <0.01).
与其他测量相比,R-LSC,R-HUI和基于体积的左侧细分 (LLS) 之间的相关性较弱.

结论:

量化肝对比度 (Q-LSC) 和肝细胞吸收指数 (HUI) 是Gd-EOB-DTPA增强的HBP成像的特征.
肝细胞吸收指数 (HUI) 取决于肝体积,左侧段影响结果.
基于ROI的量化肝对比 (R-LSC) 是一种简单有效的肝胆阶段评估方法.

关键词:

肝细胞吸收指数是什么意思左侧侧面部分部分.肝脏肝脏肝脏肝脏磁共振成像技术磁共振成像技术量化肝脏对比度量化肝脏对比度

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