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相关概念视频

In Vitro Fertilization01:24

In Vitro Fertilization

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In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
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Uterine Tubes01:16

Uterine Tubes

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The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
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Birth Control Methods01:22

Birth Control Methods

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Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
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Meiosis II01:57

Meiosis II

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Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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相关实验视频

Updated: May 22, 2025

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
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在子宫内进行治疗.

Ingo Gottschalk1, Eva Christin Weber1, Ivonne Bedei2

  • 1Department of Obstetrics and Gynecology, Division of Prenatal Medicine, Gynecological Sonography and Fetal Surgery, University of Cologne, Köln, Germany.

Ultraschall in der Medizin (Stuttgart, Germany : 1980)
|March 14, 2025
PubMed
概括

产前干预已经取得了重大进展,但存在风险. 本综述涵盖了胎儿在子宫内可治疗的疾病,以及支持这些子宫内疗法的证据.

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Last Updated: May 22, 2025

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科学领域:

  • 医学科学 医学科学 医学科学
  • 胎儿医学 胎儿医学
  • 手术创新 在外科创新.

背景情况:

  • 自20世纪70年代以来,子宫内干预已经发展,在专门中心的频率增加.
  • 尽管有进展,但产前手术对胎儿和母亲都有很大的风险.
  • 干预通常是为危及生命的胎儿疾病保留的,如果不治疗,胎儿产后预后不好.

研究的目的:

  • 为提供适合宫内治疗的胎儿状况的概述.
  • 审查支持各种产前干预措施的证据.
  • 要突出临床试验中严格评估的干预措施的数量有限.

主要方法:

  • 审查关于子宫内干预的现有文献.
  • 对特定胎儿疾病和治疗方法的证据分析.
  • 通过受控试验确定具有已确定的疗效的条件.

主要成果:

  • 产前干预的范围和应用已经大大扩大.
  • 支持产前干预的受控临床试验仍然有限.
  • 已确立的成功干预措施包括治疗胎儿输血综合征的激光疗法,脊柱裂关闭,以及对先天性隔膜的气管封闭.

结论:

  • 由于子宫内干预的固有风险,仔细选择患者至关重要.
  • 需要进一步的研究和受控试验来验证更多的产前疗法.
  • 激光疗法,脊柱裂修复和气管封闭是成功宫内干预的关键领域.