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中心肺栓塞与外周肺栓塞的特征,治疗方法和结果:一个回顾性队列研究
Hasan M Al-Dorzi1, Faisal M Almutawa2, Bader A AlRuhaymi2
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, and Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia. aldorzih@yahoo.com.
在急性肺栓塞 (PE) 中的中央血栓位置与死亡率的增加没有关联,尽管风险分类更高. 这项研究比较了住院患者中中心和外围PE的结果.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 放射学 放射学是一门学科.
背景情况:
- 在急性肺栓塞 (PE) 中血栓位置的预后意义仍在争论中.
- 了解中央和外围PE之间的差异对于患者管理至关重要.
研究的目的:
- 为了比较中央和外围急性肺栓塞的住院患者的特征和结果.
- 确定中心血栓位置是否是急性PE死亡率的独立预测因素.
主要方法:
- 在2016年至2022年期间,通过CT肺血管造影诊断出急性PE的438名住院患者的回顾性分析.
- 患者人口统计学,生物标志物水平,成像检测结果 (右心室菌株),治疗方式和中心和外围PE组之间的死亡率的比较.
主要成果:
- 中心PE患者表现出较高的素I和BNP水平,以及更频繁的右心室菌株 (72.1%与33.3%对比).
- 较高比例的中心PE患者被归类为中等高/高风险 (63.3%对24.4%).
- 尽管存在这些差异,但所有原因的医院死亡率相似 (5.3%中央与6.6%外围),中央PE与多变量分析的死亡率增加无关.
结论:
- 虽然中央PE与更多的严重性指标和更高的风险分类有关,但它不能独立预测增加的医院死亡率.
- 仅仅是血栓的位置可能不是急性肺栓塞死亡率的确切预后因素.
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