结核性淋巴腺炎中细胞形态模式与微生物学研究的相关性
Yasmeen Khatib1, Vaz G Sheldon2, Jayashri Chaudhari3
1Professor, Department of Pathology, Hinduhrudaysamrat Balasaheb Thackarey Medical College and Dr Rustom Narsi Cooper Municipal General Hospital, Mumbai, Maharashtra, India.
诊断结核淋巴炎需要将精细针吸入细胞学与微生物学测试相结合,例如基于子的核酸放大测试 (CBNAAT) 和菌生长指标管培养 (MGIT),以提高准确性.
科学领域:
- 医学微生物学 医学微生物学
- 细胞病理学 细胞病理学
- 传染性疾病 传染性疾病
背景情况:
- 精细针吸入细胞学 (FNAC) 是疑似结核淋巴腺炎的主要诊断工具.
- 微生物学测试对于诊断确认和耐药性至关重要,但通常具有较低的个体敏感性.
研究的目的:
- 分析结核性淋巴腺炎中的细胞形态学模式.
- 为了比较Ziehl-Neelsen (ZN) 染色,Auramine-Rhodamine (AR) 染色,Mycobacterium生长指标管培养 (MGIT) 和基于子的核酸放大测试 (CBNAAT) 的诊断性能.
主要方法:
- 一项前性研究涉及100例临床怀疑的结核淋巴腺炎病例,接受FNAC.
- 对细胞形态学,ZN染色,AR染色,MGIT和CBNAAT的细胞学材料的分析.
主要成果:
- 在100例病例中,有94例确诊的结核淋巴腺炎具有不同的细胞形态模式.
- 微生物学测试的阳性率:AR染色 (17.02%),ZN染色 (7%),CBNAAT (45.74%),MGIT (59.57%). 微生物学测试的阳性率是:AR染色 (17.02%),ZN染色 (7%),CBNAAT (45.74%),MGIT (59.57%). 微生物学测试的阳性率是:AR染色 (17.02%),ZN染色 (7%),CBNAAT (45.74%),MGIT (59.57%) 等.
- 结合细胞形态学和微生物学测试,获得了94.7%的灵敏度.
结论:
- 对结核性淋巴腺炎的个人微生物学测试显示敏感性有限.
- 建议将细胞形态学与CBNAAT和MGIT结合起来,以实现最佳的诊断和管理.
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