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结合面对面的实验室会议和计算机模拟,有效地教导基因编辑和DNA测序的本科遗传学学生

Chris Della Vedova¹, Gareth Denyer², Maurizio Costabile¹

¹Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

|March 15, 2025

概括

结合在线模拟与面对面 (F-2-F) 实验室的混合教学方法改善了本科遗传学教育. 这种方法提高了学生的表现和参与基因编辑和DNA测序技术.

科学领域:

遗传学教育遗传学教育
分子生物学分子生物学
生物技术是生物技术.

背景情况:

传统的遗传学实验室指导提高了参与度和实践技能,但面临着资源限制.
基因编辑和DNA测序等尖端技术需要专门的,往往资源密集的实验室经验.
开发创新的教学方法对于有效的遗传学教育至关重要.

研究的目的:

评估一种混合教学方法,将在线模拟与面对面 (F-2-F) 实验室会议相结合,用于本科生遗传学.
评估基于Unity的模拟对学生学习,参与和对基因编辑和DNA测序的看法的影响.
确定模拟使用是否能提高学生在课程基础的本科研究经验 (CURE) 中的表现.

主要方法:

开发了一个基于Unity的在线模拟来练习DNA测序技术.
将模拟集成到一个专注于酵母中的CRISPR/Cas9基因编辑的CURE中.
通过作业,访问日志和调查评估学生的表现,参与度和感知.

主要成果:

使用模拟的学生,特别是那些多天参与的学生,表现明显更好.
调查显示,学生们发现模拟是现实的,相关的,并提高了他们对DNA测序的理解.
学生对DNA测序知识的信心显著增加,对程序理解和准备情况的积极反.

结论:

将在线模拟与F-2-F实验室会议相结合,为遗传学教育中的后勤挑战提供了可行的解决方案.
这种混合方法提供了真实的,可重复的经验,复杂的技术,如基因编辑和DNA测序.
这些发现支持模拟的潜力,以增强本科生在遗传学和分子生物学方面的学习.

关键词:

克里斯普尔是什么意思?克里斯普尔是什么意思?在DNA测序过程中,DNA测序遗传学遗传学遗传学是一个混合教学方法混合教学方法基于模拟的学习.本科生本科生本科生

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