将边缘化人口纳入HPV疫苗建模的方法方法方法:系统性审查
Jennifer C Spencer1, Juan Yanguela2, Lisa P Spees3,4
1Department of Population Health, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
概括
这项研究审查了30个人类乳头瘤病毒 (HPV) 疫苗接种模型,发现了包括边缘化人口在内的各种方法. 研究人员建议对假设进行透明化,并对HPV疫苗公平模型进行更多验证.
科学领域:
- 卫生经济学和结果研究研究.
- 数学建模的数学建模
- 公共卫生 公共卫生
背景情况:
- 决策模式可以通过包括边缘化人口来改善健康公平.
- 将这些组合纳入模型结构和数据中需要具体的假设.
- 人类乳头瘤病毒 (HPV) 疫苗决策模型的方法方法需要描述.
研究的目的:
- 描述用于将边缘化人口纳入HPV疫苗决策支持模型的替代方法方法.
- 确定HPV疫苗接种模型中使用的常见策略和假设.
- 突出在模拟股权方面需要改进的领域.
主要方法:
- 系统的文献搜索 (PubMed,CINAHL,Scopus,Embase,2006年1月至2022年6月) 进行.
- 确定了HPV疫苗接种精炼投入的模拟模型,用于边缘化人口.
- 提取了关于分层,模型结构,差异归因,校准,验证和敏感性分析的数据.
主要成果:
- 30个模型按性行为,艾滋病毒状况,种族,种族,收入或农村地区分层输入.
- 确定了五种常见的方法,重点关注性行为,癌症发病率,查/护理机会或HPV自然史.
- 很少有模型对边缘化群体进行敏感性分析或验证结果.
结论:
- 在HPV疫苗模型中,建模者必须明确对HPV疫苗模型中边缘化人口的假设和理论.
- 需要更多地强调模型验证和严格的灵敏度分析.
- 对模型结构和数据假设的透明度对于以股权为中心的建模至关重要.
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