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体/HA复合体中的凝到凝的过渡,用于MMP-9激活的透到瘤球状体

Shi Yang1, Xiuli Xu1, Meixin Wang1

  • 1State Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.

ACS applied materials & interfaces
|March 15, 2025
PubMed
概括

研究人员开发了一种新型的/酸协系统,该系统在对矩阵金属蛋白酶9 (MMP-9) 的反应中从固体转化为液体. 这项创新增强了药物输送到瘤细胞和球状体,有望向癌症治疗.

关键词:
协类动物 协类凝到可可的过渡过程矩阵金属蛋白酶9 (MMP-9) 的作用.阶段分离可以分离相位.瘤球体是瘤球体.

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Matrix metalloproteases (MMPs) are enzymes involved in the hydrolysis of proteins and glycoproteins of the extracellular matrix. MMPs are essential for the migration and proliferation of cells through the dense matrix network, throughout embryonic development, and throughout morphogenesis. The first MMP activity discovered was a collagenase in a tadpole's tail undergoing metamorphosis. The active collagen deposition and modifications lead to the morphogenesis of tadpoles into the adult body.
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