优化和稳定格拉尼奥尔纳米乳液稳定协同使用混合生物活性剂系统的萨宁和莱西的稳定
Amit Kumar1,2, Michael Gradzielski2, Rohini Kanwar3
1Department of Chemistry and Centre for Advanced Studies in Chemistry, Panjab University, Chandigarh 160014, India.
Langmuir : the ACS journal of surfaces and colloids
|March 15, 2025
概括
诸如萨波宁和大豆莱西丁之类的生物表面活性剂可以为农业食品用途制造稳定的精油纳米乳液. 二元混合物增强对盐和pH值变化的稳定性,提供绿色纳米载体解决方案.
科学领域:
- 农业科学 农业科学
- 合体和表面化学
- 纳米技术纳米技术
背景情况:
- 精油 (EO) 越来越多地用于农业食品应用.
- 开发稳定的纳米乳液 (NE) 对于它们的有效输送至关重要.
- 生物表面活性剂为合成乳化剂提供了一种绿色替代品,用于NE配方.
研究的目的:
- 使用生物表面活性剂制备和稳定基拉尼油在水 (O/W) 纳米乳液 (NEs).
- 调查沙波宁和大豆-莱西丁混合物的协同作用对NE特性.
- 评估这些NE在各种环境压力因素下的稳定性.
主要方法:
- 纳米乳液 (NEs) 是用geraniol精油制成的,并通过超声波稳定.
- 作为乳化剂,采用了沙波宁和大豆莱西生物表面活性剂的组合.
- 在不同的储存条件,盐度和pH值变化下评估了NE的稳定性.
主要成果:
- 乳素稳定NE的油与表面活性剂比 (OSR) 为2:1显示出最小的尺寸 (72.8nm水力动力半径,13.5%PDI).
- 莱西丁和沙波宁的二元混合物表现出协同效应,产生具有水力动力半径低于50 nm和PDI<20%的NE.
- 配备了3:1和1:1的莱西丁-沙宁比率的NE在盐度高达300毫米和pH范围为4-10的相分离下保持稳定.
结论:
- 二元生物表面活性剂混合物显示出协同相互作用,以增强纳米乳液的形成和稳定性.
- 开发的NE在各种环境条件下显示出有希望的稳定性,适合农业食品应用.
- 这些发现支持使用生物表面活性剂组合开发长期稳定的绿色纳米乳液.
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