树脂矩阵复合材料在牙科临床环境中的毒性
Maria Cordeiro1, Júlio C M Souza1,2,3,4, Ana T P C Gomes1,2
1Faculty of Dental Medicine, Universidade Católica Portuguesa, Estrada da Circunvalação, 3504-505, Viseu, Portugal.
Odontology
|March 15, 2025
概括
这次系统性审查发现树脂矩阵复合材料的毒性较低,但适当的处理和光固化对于最大限度地减少残留单体和潜在的健康风险至关重要.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料 牙科材料
- 毒理学 毒理学 毒理学
背景情况:
- 树脂矩阵复合材料广泛用于修复性牙科.
- 人们对其潜在的毒性存在担忧,这是由于可浸的组件造成的.
- 了解影响复合毒性的因素对于患者安全至关重要.
研究的目的:
- 系统地审查导致患者树脂矩阵复合物毒性的因素.
- 评估有关牙科复合材料局部和全身毒性的现有证据.
- 确定最佳实践,以尽量减少复合材料相关的不良影响.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在PubMed,Cochrane Central和科学网上进行全面的文献搜索.
- 包括过去20年内以英语出版的12项体内研究.
主要成果:
- 在唾液,尿液和血液样本中发现了可检测的自由单体水平.
- 在体内研究表明局部和全身毒性相对较低.
- 操作者依赖的因素和遵守制造商指导方针显著影响材料特性和单体释放.
结论:
- 虽然目前的证据表明毒性低,但检测方法的技术限制需要进一步研究.
- 严格遵守标准的椅子侧指南和适当的光固化是至关重要的.
- 树脂矩阵复合材料的适当处理和聚合将残留单体释放和潜在的毒性降至最低.
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