在急性髓性白血病患者亚组中,对SYK抑制剂具有高和低敏感性的基因表达概况

Marte Karen Brattås1,2, Franziska Görtler3, Silje Johansen1,4

  • 1K.G. Jebsen Center for Myeloid Malignancies, Institute of Clinical Science, University of Bergen, Bergen, Norway.

Hematological oncology
|March 15, 2025
PubMed
概括

腺氨酸激酶 (SYK) 抑制剂在急性髓性白血病 (AML) 患者样本中表现出不同的有效性. 基因表达分析确定了不同的特征,预测对SYK抑制剂的高或低敏感性,为个性化AML治疗铺平了道路.

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