在COPD的循环运动期间吸入薄荷来缓解呼吸不良:一项随机试验
Michele R Schaeffer1, Lucas Vanden Bossche2, Kaat Beckers1
1Research Group for Rehabilitation in Internal Disorders, Department of Rehabilitation Sciences, Leuven, Belgium.
薄荷吸入 (MI) 减少了COPD患者在运动期间的呼吸不适. 虽然并没有改善炼时间,但MI使得大多数参与者更容易感觉到吸气气流.
科学领域:
- 肺部医学 肺部医学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 众所周知,薄荷吸入 (MI) 可以减少COPD的紧张呼吸和健康人群的运动期间的呼吸不良.
- 拟议的机制包括冷受体刺激,调节呼吸努力感知和空气流.
研究的目的:
- 调查薄荷吸入 (MI) 是否可以缓解慢性阻塞性肺部疾病 (COPD) 患者的运动性呼吸障碍.
主要方法:
- 20名COPD患者接受了两次持续负荷循环炼测试,直到疲.
- 测试是用薄荷醇或安慰剂 (草调味) 进行的,顺序是平衡的.
- 呼吸障碍的强度,不愉快度和感官质量使用博格尺度和多维呼吸障碍概况进行了评估.
主要成果:
- 与安慰剂相比, Menthol 吸入显著降低了连续性呼吸障碍强度评级 (P = .01).
- 呼吸障碍不愉快,空气饥饿和精神呼吸努力的评分在运动结束时降低了 (P < .05).
- 薄荷醇没有影响呼吸道或神经肌肉的参数或炼耐力时间.
结论:
- Menthol 吸入可能是对某些 COPD 患者的运动性呼吸障碍有益的管理策略.
- 建议进行进一步的研究,以探索MI在改善COPD运动康复结果方面的潜在作用.
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