吸烟对眼表面健康和角膜神经指标产生负面影响
Ansa Anam1, Mingyi Yu2, Chang Liu2
1Department of Ophthalmology, MTI Khyber Teaching Hospital, Peshawar, Pakistan.
The ocular surface
|March 15, 2025
概括
吸烟会严重损害眼睛表面,减少角膜神经密度,损害撕裂膜的稳定性. 这项研究揭示了对吸烟者的角膜神经,上皮和免疫细胞的有害影响.
科学领域:
- 眼科医生 眼科 眼科
- 眼睛表面疾病 眼睛表面疾病
- 角质神经生物学 角质神经生物学
背景情况:
- 吸烟是一种普遍的习惯,已知有系统性健康影响.
- 吸烟对眼表面健康的影响,特别是角膜神经的结构和功能,需要详细的研究.
研究的目的:
- 综合评估吸烟对眼睛表面的影响.
- 分析吸烟者与非吸烟者的角膜神经,角膜上皮,树突细胞 (DC) 和临床参数的变化.
主要方法:
- 一项涉及250名吸烟者和272名非吸烟者的横截面研究.
- 在体内共聚焦显微镜评估角膜神经,上皮和DCs.
- 眼皮表面的评估包括眼破裂时间 (TBUT),染色,敏感性和希尔默测试;眼皮表面疾病指数 (OSDI) 问卷查询症状.
主要成果:
- 吸烟者显著减少角膜神经纤维密度,长度和面积,更长的吸烟时间与更大的神经损失相关.
- 在吸烟者中观察到角膜神经胀增加,树突细胞密度和数量增加,眼破裂时间缩短.
- 吸烟者表现出较高的眼睛表面染色分数,这表明眼睛表面完整性受到损害.
结论:
- 吸烟导致角膜神经形态和数量的显著变化.
- 吸烟会增加角膜中的免疫细胞,并损害眼睛表面的整体完整性.
- 这些发现强调了吸烟对眼睛健康的有害影响,需要戒烟干预措施.
更多相关视频
09:31Determining the Toxicity of UV Radiation and Chemicals on Primary and Immortalized Human Corneal Epithelial Cells
Published on: July 22, 2021
2.0K
09:50Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
11.1K
相关概念视频
Stress Prevention and Stress Management Techniques IV
23
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
23
Glaucoma: Overview
488
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
488
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
2.7K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
2.7K
Accessory Structures of the Eye
1.4K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.4K
