在美国ECHO计划中,出生时的儿童机会指数和喘与反复恶化的喘
Rachel L Miller1, Holly Schuh2, Aruna Chandran2
1Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
The Journal of allergy and clinical immunology
|March 15, 2025
概括
患有反复恶化的儿童喘 (ARE) 在机会较低的社区更高. 这种风险在年轻的少数民族儿童中最大,这表明喘发病率存在持续的种族差异.
科学领域:
- 环境健康 环境健康
- 儿童喘研究 儿童喘研究
- 健康的社会决定因素
背景情况:
- 儿童喘受环境暴露和社会决定因素的影响.
- 特定的喘表型可能与邻里条件有关.
- 了解这些联系对于公共卫生干预至关重要.
研究的目的:
- 调查出生时邻居机会与喘与复发性恶化 (ARE) 发病率之间的联系.
- 为了测试儿童机会指数 (COI) 影响ARE发病率 (IRs) 的假设.
主要方法:
- 对来自ECHO计划的15877名儿童 (1990年至2018年出生) 的分析.
- 在出生时评估儿童机会指数 (COI).
- 评估父母报告的种族/种族和人口统计数据作为效果修饰因素.
主要成果:
- 在COI非常低的社区出生的孩子有更高的ARE IR (10.98).
- 在所有COI类别中,非西班牙裔黑人 (NHB) 儿童的发病率高于非西班牙裔白人儿童.
- 低COI地区的NHB和西班牙裔黑人儿童的ARE IR比白人儿童高几倍.
结论:
- 在资源不足的社区,特别是年轻的少数群体儿童,父母有喘病史的儿童,ARE的发病率较高.
- 喘风险的种族差异仍然存在,即使在较高的COI社区,这表明种族本身是风险因素.
- 需要针对弱势群体进行有针对性的干预,以应对环境和社会对儿童喘的影响.
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