在对"偶然"巴雷特食道的基于人群的分析中,患有失育症的高率
Jennifer M Kolb1, Christian Davis2, J Lucas Williams3
1Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Greater Los Angeles VA Healthcare System, Los Angeles, California.
概括
偶然的巴雷特食道 (BE) 几乎和专门的查一样经常被发现. 这种情况表现出类似或更高风险的特征,这表明精确的查可以识别更多高风险病例.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 内镜检查是指内镜检查.
背景情况:
- 目前的巴雷特食道 (BE) 查和监测错过了许多食道腺癌.
- 新的测试可能会扩大BE查的指示,但这需要了解偶然发现的BE的特征和进展风险.
- 本研究分析了国家数据,以描述偶然的BE.
研究的目的:
- 通过使用国家基准数据,偶然发现的巴雷特食道 (BE) 的特征.
- 为了比较偶然的BE,BE查和BE监测之间的人口统计,疾病特征和发育不良检测率 (DDR).
- 评估对BE管理的质量指标的遵守.
主要方法:
- 来自GI质量改进联盟 (GIQuIC) 登记处的BE上部内镜病例分析 (2015年1月~2022年7月).
- 根据症状分类的病例:BE查,监测或偶然 (与BE无关).
- 人口统计数据的比较,BE段长度,DDR (低度和高度发育不良),以及对质量指标的坚持.
主要成果:
- 在88370个BE病例中,16.4%是偶然的,几乎与查 (18.6%) 相匹配.
- 与查 (3.3%) 和监测 (2.5%) 相比,偶然的BE具有更长的段长 (2.9厘米) 和最高的DDR (3.8%).
- 在偶然和查BE (54.5%,51.9%) 与监测 (73.6%) 相比,对适当监测的遵守率较低.
结论:
- 偶然的巴雷特食道 (BE) 是常见的,发现的速度与专门的查检查相似.
- 偶然的BE表现出与传统查/监测人群相比具有相似或更糟糕的高风险特征 (细分长度,发育不良产量).
- 改进BE查计划可以识别具有重大进展风险的病例,类似于当前的方法.
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