管理与怀孕相关的乳腺癌:一种实用的方法
Prarthna V Bhardwaj1, Yara Abdou2
1Assistant Professor of Medicine, Division of Hematology-Oncology, University of Massachusetts Chan School of Medicine - Baystate, Springfield, MA, USA.
Seminars in perinatology
|March 15, 2025
概括
怀孕相关乳腺癌 (PABC) 的诊断往往会延迟. 管理平衡孕产妇/胎儿风险,在晚期的三个月内进行化疗,并在怀孕期间避免放射/内分泌疗法.
科学领域:
- 在瘤学瘤学.
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 怀孕相关的乳腺癌 (PABC) 是罕见的.
- 由于怀孕期间和分娩后乳房的生理变化,诊断具有挑战性.
- 在PABC中,出现了独特的临床和伦理困境.
研究的目的:
- 概述PABC诊断和管理的复杂性.
- 审查平衡孕产妇和胎儿福祉的治疗方式.
- 突出多学科护理和支持的重要性.
主要方法:
- 对PABC诊断和治疗策略的文献综述.
- 对化疗,手术,辐射和内分泌治疗的考虑分析.
- 讨论道德和心理社会方面的问题.
主要成果:
- 延迟诊断是常见的,由于怀孕相关的乳腺变化掩盖了诊断.
- 化疗,主要是人环素,在第二和第三季度被认为更安全.
- 辐射,内分泌和大多数向疗法在怀孕期间是禁忌的.
结论:
- PABC需要一种多学科的方法来平衡孕产妇和胎儿的安全.
- 治疗时间和治疗方式的选择至关重要.
- 对于受影响的母亲和家庭来说,全面的心理社会支持是必不可少的.
相关概念视频
Disorders of the Female Reproductive System
286
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
286
Cancer Survival Analysis
315
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
315
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K
Tumor Progression
6.2K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.2K
Pneumonia V: Nursing management and Prevention
1.8K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
1.8K
Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K


