在小孩接受重大神经外科手术后的手术内同位素平衡与假定性晶体在手术后的稳定:一个随机对照试验
Mao-Wei Xing1,2, Yue Zhang1, Hui-Ting Zhu1
1Department of Anesthesiology, Peking University First Hospital, Beijing, China.
BMC pediatrics
|March 16, 2025
概括
在儿科神经外科手术中使用手术内同位素平衡液 (IB) 的结果显示,与低压溶液 (H) 相比,的变化较少. 虽然在统计学上显著,但对稳态和血红蛋白水平的临床影响是最小的,因此需要对潜在波动保持谨慎.
科学领域:
- 儿科麻醉学和重症监护
- 神经临界护理是指神经临界护理.
- 流体管理和电解质平衡
背景情况:
- 小儿神经外科手术中关于平衡的最佳手术内维护液尚未确立.
- 接受重大神经外科手术的小孩子特别容易受到液体和电解质干扰.
研究的目的:
- 调查手术内同位素平衡维护液是否与接受重大神经外科手术的儿科患者的平衡变化较小有关.
- 为了比较同位素平衡 (IB) 与低位素 (H) 溶液对神经外科手术后血清电解质水平的影响.
主要方法:
- 随机对照试验涉及接受重大神经外科手术的儿科患者 (长达6岁).
- 患者接受了同位素平衡 (IB) 或0.2%低位素 (H) 溶液作为手术内维护液.
- 血清电解质水平从手术前的基线监测到手术后的6天.
主要成果:
- 与H组相比,IB组从手术结束到术后24小时的血清变化明显较小.
- 在IB组中较少的患者在术后24小时经历了显著的下降 (>2.5 mmol/l) (33% vs 63%).
- 在手术后48小时,IB组的血红蛋白水平较高,尿液流量较少;没有报告任何不良的神经或循环症状.
结论:
- 在小儿神经外科手术患者的手术内同位素平衡溶液输液导致了统计学上,但不是临床上,小儿神经外科手术患者的平衡和术后血红蛋白水平的最小变化.
- 建议对同位素平衡维护液的潜在过度波动保持谨慎,即使是短时间输液.
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