在我们所有人的研究计划中使用电子烟和发生心脏代谢条件
John Erhabor1,2, Zhiqi Yao1, Erfan Tasdighi1
1Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease, Baltimore, MD, USA.
专用电子烟使用与30-70岁成年人中COPD和高血压有关. 可燃性香烟的使用和双重使用显示出与多种心脏代谢疾病的强烈关联.
科学领域:
- 心血管健康 心血管健康
- 肺部病理学 肺部病理学
- 代谢健康 代谢健康
背景情况:
- 电子烟对心脏代谢疾病的健康影响尚未得到充分证实.
- 需要进行研究来了解与各种烟草制品使用模式相关的风险.
研究的目的:
- 调查专用电子烟使用 (EE),专用可燃香烟使用 (ECC) 和双重使用 (DU) 与发生心脏代谢条件之间的关联.
- 提供有关新型烟草产品的监管政策的证据.
主要方法:
- 利用了来自"我们所有人"研究计划的纵向数据 (N=249,190).
- 根据人口统计学和BMI调整的员工考克斯回归分析.
- 使用ECC作为阳性对照来验证发现.
主要成果:
- 在30-70岁的成年人中,EE与COPD (aHR 2.29) 和高血压有显著的关联 (aHR 1.39).
- ECC和DU与高血压,2型糖尿病 (T2DM),COPD,心力衰竭 (HF) 和动脉样硬化心血管疾病 (ASCVD) 有着强烈的关联.
- 双重使用表明ASCVD的风险可能更高 (aHR 2.18).
结论:
- 单独使用电子烟与特定年龄组的COPD和高血压有关.
- 燃烧性香烟的使用和双重使用对多种心脏代谢疾病构成重大风险.
- 调查结果为有关电子烟和其他烟草制品的公共卫生建议和监管决定提供了信息.
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