隐藏的危险:静脉注射添加剂中的微塑料及其进入身体的途径
Anushree Pal1, Sukalyan Chakraborty2
1Department of Civil and Environmental Engineering, Birla Institute of Technology, Ranchi, Jharkhand, 835215, India.
Environmental monitoring and assessment
|March 16, 2025
概括
微塑料 (MP) 存在于储存在塑料袋中的医疗IV液体中. 长时间储存会增加MP的污染,在医疗治疗期间可能对健康构成风险.
科学领域:
- 环境科学 环境科学
- 材料科学 材料科学 材料科学
- 公共卫生 公共卫生
背景情况:
- 微塑料 (MPs) 的污染在环境领域和人体组织中广泛存在.
- 已知MP在商业产品中的来源,但其在医疗治疗中的存在尚未得到充分研究.
- 静脉注射 (IV) 添加剂储存在塑料容器中,引发了对潜在的MP漏的担忧.
研究的目的:
- 调查静脉注射 (IV) 添加剂中微塑料的存在和特征.
- 为了确定存储时间是否会影响塑料IV容器中的MP释放.
- 为了确定在IV溶液中发现的构成MP的聚合物类型.
主要方法:
- 使用立体显微镜检测和量化MP的11种IV添加剂的分析.
- 使用微福里埃变换红外光谱 (FTIR) 进行MP大小,形态 (纤维和碎片) 和聚合物组成的表征.
- MP 丰度与储存时间和容器表面状况的相关性.
主要成果:
- 在所有分析的IV添加剂中检测到MPs的显著存在,主要是纤维和碎片 (<100μm).
- 已识别的聚合物包括聚烯-聚乙烯 (PP-PE) 共聚合物,聚烯 (PP) 同聚合物,聚烯 (PVP) 和聚氨 (PU).
- 随着更长的储存时间,观察到增加的MP丰度和容器表面粗度,表明材料降解.
结论:
- 输液添加剂代表了微塑料直接进入人体的被忽视的暴露途径.
- 储存期间塑料容器的降解有助于医学溶液的MP污染.
- 由于IV治疗的广泛使用,对健康风险和监管措施的进一步研究至关重要.
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