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Updated: May 22, 2025

Quantitative Analysis of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Stabilization in a Neural Model of Alzheimer's Disease (AD)
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Published on: January 10, 2025

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PPM1D通过促进线粒细胞吸收来改善阿尔茨海默病

Aiming Wang1, Fan Zhang2, Wenqiang Zhang3

  • 1Department of Neurology, Tieling Central Hospital, Tieling, Liaoning, People's Republic of China; Department of Neurology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.

Experimental neurology
|March 16, 2025
PubMed
概括

蛋白酸酶PPM1D增强了细胞清洁过程 - - 细胞食,以对抗阿尔茨海默病的进展. 在小鼠和神经元中恢复PPM1D水平改善了认知功能并减少了疾病病理.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.线粒细胞衰变 (mitophagy) 是一种细胞衰变的过程.神经元受损的情况.神经毒性 神经毒性在PPM1D中,它是PPM1D.

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