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Updated: May 22, 2025

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前列腺素E2通过EP4/cAMP/IKK/NF-κB通路缓解炎症反应和肺损伤

Yelin Tang1, Weiting Pan2, Wenting Ding2

  • 1Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325600, China; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China; Guangdong Food and Drug Vocational College, Guangzhou, Guangdong 510520, China.

Biochimica et biophysica acta. Molecular basis of disease
|March 16, 2025
PubMed
概括

前列腺素E2 (PGE2) 通过EP4信号来抑制IKK/NF-κB通路来减少炎症. 这一发现支持PGE2作为急性肺损伤 (ALI) 和败血症的潜在治疗方法.

关键词:
急性肺损伤是什么?急性肺损伤是什么?脂聚糖类糖化物 脂聚糖类糖化物在 NF-κBB 中.前列腺腺素E2是什么败血症 这是一种败血症.

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