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乳腺的desmoid型纤维化:一个病例报告

Wen-Yong Ren¹, Hao Su¹, Wei Guo²

¹Breast Surgery Department, General Surgery Center, First Hospital of Jilin University, 130021 Changchun, Jilin, China.

Annali italiani di chirurgia

|March 16, 2025

概括

德斯莫伊德型纤维瘤 (DTF) 是一种罕见的乳腺瘤. 这个案例突出了一个年轻女子成功接受了乳房切除术,在12个月后没有复发.

科学领域:

在瘤学瘤学.
病理学病理学病理学
放射学放射学是一门学科.

背景情况:

德斯莫伊德型纤维瘤 (Desmoid-type fibromatosis,DTF) 是一种罕见的,局部具有攻击性的良性乳腺瘤.
已知DTF具有透性生长和局部复发,但缺乏转移潜力.

研究的目的:

在一个年轻的女人身上呈现一种desmoid类型纤维素瘤病例.
讨论DTF的诊断挑战和管理.

主要方法:

案例介绍一个年轻的女人有明显的乳房质量.
诊断工作包括成像 (BI-RADS类别4+) 和超声波引导的核心针活检.
管理涉及扩大乳腺切除术,随后进行监视.

主要成果:

最初的成像表明恶性瘤,但活检显示良性增生.
手术后的病理学证实了desmoid类型的纤维素瘤.
在手术后12个月的随访中没有观察到复发或转移.

结论:

DTF可能会带来诊断挑战,在成像上模仿恶性瘤.
随着监视后的外科治疗对DTF可能是有效的.
早期诊断和适当的治疗对于管理DTF至关重要.

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Desmosomes

Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...