新发型1型糖尿病中的过渡性甲状腺功能障碍:重新评估测试时间以获得准确的结果
Talha Üstüntaş1, Mehmet Emre Atabek2, Beray Selver Eklioğlu2
1Department of Pediatrics, Necmettin Erbakan University, Konya, Türkiye.
Turkish archives of pediatrics
|March 17, 2025
概括
患有新发型1型糖尿病 (T1DM) 的儿童的甲状腺功能通常在两周内恢复正常. 对于那些已经有甲状腺疾病或症状的人来说,建议立即进行甲状腺检测.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 糖尿病学 糖尿病学
- 甲状腺学 甲状腺学
背景情况:
- 1型糖尿病 (T1DM) 是一种常见的儿童内分泌疾病,需要全面管理.
- 甲状腺功能障碍是T1DM患者已知的并发症.
- 在新诊断的T1DM中了解甲状腺功能的时间动态对于适当的临床护理至关重要.
研究的目的:
- 为了确定儿童T1DM患者诊断时甲状腺功能障碍的患病率.
- 通过定期监测来调查长期的甲状腺功能状态.
- 为了在这个人群中确定甲状腺功能测试的最佳时间.
主要方法:
- 对208名新诊断T1DM的儿科患者进行了回顾性队列研究.
- 医疗记录的分析,包括人口统计,临床表现,实验室发现和甲状腺功能测试.
- 随着时间的推移,定期监测甲状腺功能.
主要成果:
- 诊断时的患病率:69.2%的甲状腺功能减退,24.5%的甲状腺功能减退综合征 (ESS),5.8%的补偿性甲状腺功能减退,0.5%的原发性甲状腺功能减退.
- 在初始评估和随访期间,甲状腺功能的显著改善被观察到 (P < .001).
- 大约76.5%的初始ESS患者在第二次访问时恢复了甲状腺功能,通常在1-2周内.
结论:
- 新诊断的T1DM儿科患者的甲状腺功能测试应在临床稳定后1-2周进行.
- 对于有甲状腺疾病史或暗示性临床症状的T1DM患者,立即进行甲状腺评估是有必要的.
- 定期监测有助于了解T1DM中某些甲状腺功能异常的短暂性质.
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