在精神病中暴力风险因素的系统审查:10年更新
Tyra Lagerberg1, Sinéad Lambe2, Anabelle Paulino3
1Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK and Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
概括
犯罪史和药物滥用是精神病患者暴力的主要风险因素. 像大麻使用这样的新因素需要进一步研究,一些因素提供了潜在的干预目标.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 犯罪学 犯罪学
- 公共卫生 公共卫生
背景情况:
- 了解精神病中的暴力风险因素对于预防和管理至关重要.
- 现有证据在很大程度上依赖于横截面数据,需要更新的审查.
- 纵向数据为识别风险因素提供了更坚实的基础.
研究的目的:
- 综合从纵向研究中关于精神病中的暴力风险因素的证据.
- 专注于精神分裂症谱系障碍,双相情感障碍或其他情感精神病患者.
- 更新以前的审查与最新的纵向研究.
主要方法:
- 搜索了五个文献数据库,直到2022年6月为纵向研究.
- 包括被诊断患有精神分裂症或其他精神病的人 (DSM/ICD标准).
- 在≥3个独立样本中报告的风险因素的随机效应元分析.
主要成果:
- 分析了47项纵向研究 (41个独立样本,203,297人).
- 犯罪史 (OR 3.50) 和药物滥用 (OR 2.36) 是显著的风险因素.
- 大麻使用 (OR 3.34) 成为一种新的风险因素;治疗因素是保护性的 (OR 0.54).
结论:
- 经过验证的犯罪史和药物滥用作为精神病中的关键暴力风险因素,使用纵向数据.
- 强调大麻使用是潜在的新风险因素,需要复制.
- 确定了几个因素作为未来干预的潜在目标.
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