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术后营养习惯和与经历胰腺突切除术的患者胃空气延迟的相关性:一项追溯观察性研究
Mikeeley Hoch1, Ingrid Hickman1,2, Thomas O'Rourke2,3
1Department of Nutrition and Dietetics, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
概括
延迟胃排空 (DGE) 影响了胰腺切除术后近一半的患者,特别是男性. DGE与更糟糕的结果和对人工营养的需求增加有关,但不是早期营养不良.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 临床营养学 临床营养学
背景情况:
- 延迟胃排空 (DGE) 是胰腺管切除术后的常见并发症.
- 它可以通过延迟营养开始,对营养状况和临床结果产生负面影响.
- 了解DGE的关联对于改善手术后护理至关重要.
研究的目的:
- 调查DGE与患者特征之间的关联.
- 探索DGE与早期手术后营养状况的关系.
- 检查DGE对澳大利亚患者营养实践和临床结果的影响.
主要方法:
- 对80名接受胰腺双管切除术的患者进行了回顾性观察性研究 (2019年1月至2022年6月).
- DGE使用胰腺外科术国际研究小组的定义进行分类.
- 统计分析包括独立的t测试,奇平方/费舍尔精确测试和多变量建模.
主要成果:
- DGE的发病率为45%,男性的发病率更高 (p=0.025).
- DGE与术后胰腺的增加相关 (p=0.03) 和严重的并发症 (Clavien-Dindo ≥3,p=0.011).
- DGE与更大的肠道/肠道营养使用 (p<0.001),更长的住院时间 (p<0.001) 和再入院 (p=0.014) 相关.
结论:
- 胰腺切除术后DGE的高发病率与人工营养的使用增加和较差的结果有关.
- 男性的性别是DGE的重要预测因素.
- 在这个队列中,早期的手术后营养不良与DGE没有显著的关联.
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