在2型糖尿病患者中评估甲状腺功能障碍及其与糖尿病并发症的关联:一个跨部门研究
Prasanna Ratilal Patel1, Aishika Maitra2, Arya Ashok3
1Department of General Medicine, Gujarat Medical Education and Research Society (GMERS) Medical College and Hospital, Valsad, IND.
Cureus
|March 17, 2025
概括
甲状腺功能低下症显著增加了2型糖尿病 (T2DM) 中微血管和宏血管并发症的风险. 在T2DM患者的常规甲状腺查对于预防糖尿病并发症至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 糖尿病学 糖尿病学
- 内部医学 内部医学
背景情况:
- 2型糖尿病 (T2DM) 是一种普遍的代谢障碍,与显著的发病率和死亡率有关.
- 甲状腺功能障碍是T2DM中常见的并发症,可能会影响糖尿病并发症的进展.
研究的目的:
- 研究甲状腺功能障碍与T2DM患者的微血管和宏血管并发症之间的关联.
主要方法:
- 进行了一项涉及200名T2DM患者 (30-70岁) 的横截面研究.
- 进行了甲状腺功能测试和糖尿病并发症 (视网膜病变,病,神经病变,PAD) 的查.
- 统计分析包括奇平方测试和多变量回归.
主要成果:
- 甲状腺功能障碍的患病率为26.5%,甲状腺功能障碍症更为常见 (84.9%).
- 甲状腺功能低下症与糖尿病视网膜病变 (OR=7.72),病变 (OR=4.87),神经病变 (OR=3.10) 和PAD (OR=8.12) 的几率增加显著相关.
- 甲状腺功能障碍与糖尿病并发症没有显著关联.
结论:
- 甲状腺功能低下是T2DM中微血管和宏血管并发症的重要危险因素.
- 将甲状腺功能评估纳入日常糖尿病护理中,可能有助于降低并发症风险.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
Diabetes: Symptoms, Diagnosis, and Complications
495
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
495
Diabetes Mellitus: Overview and Type I Subtype
2.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.3K
Carbohydrate Metabolism
10.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.7K
Diabetes: Management and Pharmacotherapy
220
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
220
Pathophysiology of Diabetes
839
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
839


