评估左心室功能障碍在患有巨病的患者使用全球纵向菌株的二维跟踪心声和组织多普勒成像通过二维跟踪心声和组织多普勒成像
Dhanachand S Nameirakpam1,2, Anupama Hegde2, Himamshu Acharya3,4
1Cardiology, Regional Institute of Medical Sciences, Imphal, IND.
Cureus
|March 17, 2025
概括
宏壮病患者表现出亚临床左心室缩功能障碍,可通过全球纵向应变 (GLS) 声心图检测到. 活跃疾病和伴随性疾病,如高血压加剧了这种情况,突出显示了对心脏监测的需要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
背景情况:
- 由于生长激素 (GH) 和胰岛素样生长因子-1 (IGF1) 过多而引起的巨,经常导致心血管并发症,增加发病率和死亡率.
- 左心室 (LV) 功能障碍是一种常见的并发症,需要敏感的检测方法.
研究的目的:
- 为了确定左心室缩功能障碍的频率,在壮病患者使用全球纵向应变 (GLS) 通过2D斑点跟踪回声心脏学.
- 用组织多普勒成像 (TDI) 来评估左心室透静功能障碍的频率.
主要方法:
- 一项横截面研究包括20名壮病患者和20名匹配对照.
- 用2D斑点跟踪回声心脏学来测量GLS.
- 组织多普勒成像 (TDI) 和传统的2D回声心脏成像评估了透缩功能.
主要成果:
- 与对照组 (-17.47±0.98) 相比,壮症患者的GLS显著降低 (-15.79±2.54),这表明LV系统功能障碍.
- 55%的壮病患者有异常的GLS. 左心室体积指数 (LAVi) 和左心室质量指数 (LVMi) 的增加与异常的GLS有关.
- 两组之间没有发现 LV 扩张功能障碍的显著差异;然而,在壮病患者中,LAVi 和 LVMi 显著更高. 巨,高血压和身体表面积预测异常的GLS.
结论:
- 通过GLS,2D斑点跟踪回声心电图有效地检测到亚临床LV静脉缩功能障碍在壮病患者.
- 活跃壮症与更明显的GLS异常,增加的LAVi和LVMi有关.
- 虽然在这个匹配的队列中,LV透析功能不显著不同,但GLS异常突显了壮病对心血管的影响.
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