侧髓综合征的延迟发病:一个病例报告
Lexi Garber1,2, LaTeya Foxx3
1Department of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine, Bradenton, USA.
Cureus
|March 17, 2025
概括
侧髓综合征 (LMS) 或瓦伦伯格综合征是一种罕见的中风. 这一案例突出显示了五天内不寻常的症状进展,强调了诊断中风的演变.
科学领域:
- 神经学 神经学
- 血管神经学 血管神经学
- 脑卒中医学 脑卒中医学
背景情况:
- 侧髓综合征 (LMS),也称为瓦伦伯格综合征,是一种罕见的后部循环中风.
- 它通常涉及后下大脑小动脉或脊椎动脉.
- 通常,LMS会呈现出一套不同的神经系统症状.
研究的目的:
- 讨论一个左侧LMS病例,症状呈现延迟.
- 在LMS的背景下强调中风演变的概念.
- 强调在诊断中考虑中风进展的重要性,即使最初的结果是负面的.
主要方法:
- 一个72岁的男性被诊断为左侧LMS的病例报告.
- 最初出现,随后五天后出现经典的LMS症状.
- 诊断基于体检,并通过重复扩散权重MRI证实.
主要成果:
- 患者在最初的头症状和经典的LMS症状出现之间经历了五天的延迟.
- 这种渐进的发作在缺血性中风中不寻常,包括LMS.
- 这一案例说明了中风的演变,症状随着时间的推移而逐渐恶化,原因是缺血或心脏病扩散的恶化.
结论:
- 在LMS和其他缺血性中风中,可以出现延迟和演变的症状.
- 临床医生必须考虑中风的演变,即使最初的诊断研究是负面的.
- 身体检查对于诊断LMS等疾病至关重要,成像提供确认.
相关概念视频
Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...


