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Updated: May 22, 2025

Modeling Chemotherapy Resistant Leukemia In Vitro
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在儿科患者的B细胞急性淋巴细胞白血病第一次复发后影响化疗反应的因素

Shu-Wan Dong1, Hong Zhang2, Jing Wang3

  • 1Department of Pediatrics, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830054, Xinjiang Uygur Autonomous Region, China.

American journal of translational research
|March 17, 2025
PubMed
概括

在儿科B细胞急性淋巴细胞白血病 (B-ALL) 复发中,化疗的有效性受白细胞计数,TNF-α和IL-6等细胞因子升高以及特定遗传变化的影响. 较高的白细胞计数具有保护作用,而增加的TNF-α和IL-6则是反应不良的危险因素.

关键词:
B细胞急性淋巴细胞白血病.抗化学疗法耐药性 抗化学疗法耐药性细胞因子 细胞因子遗传变化 遗传变化最少残留疾病的最小残留疾病.儿科瘤学 儿科瘤学

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