电子烟:安全的工具还是口腔癌的风险因素? 一个系统的审查
Gaspare Palaia1, Mohamed Mohsen1, Daniele Pergolini1
1Department of Oral and Maxillo-Facial Sciences, University of Rome "Sapienza", Via Caserta, 6, Rome, 00161, Italy.
Journal of clinical and experimental dentistry
|March 17, 2025
概括
电子烟 (e-cigarettes) 可能对口腔健康构成风险,包括细胞损伤和粘膜病变. 需要进一步的研究才能充分了解与电子烟使用相关的长期口腔癌风险.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 毒理学 毒理学 毒理学
背景情况:
- 电子烟 (e-cigarettes) 由于被认为是安全的,因此越来越受欢迎.
- 电子烟对口腔健康的长期影响在很大程度上是未知的.
- 潜在的风险包括细胞损伤,遗传不稳定性和粘膜病变.
研究的目的:
- 审查有关电子烟作为口腔癌风险因素的现有文献.
- 综合临床和体外研究的发现.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在PubMed和Scopus上使用关键词进行的搜索:"电子烟"",口腔癌"",风险因素".
- 包括12项研究 (6项临床,6项体外) 在符合资格查后;质量和偏差风险评估.
主要成果:
- 涉及413名参与者的临床研究表明,与电子烟使用相关的粘膜病变和遗传不稳定性.
- 试验室研究显示偏差的风险较低或未知.
- 没有研究报告工业赞助.
结论:
- 电子烟使用与潜在的口腔健康风险有关.
- 有限的长期数据和相互矛盾的结果需要进一步的研究.
- 建议进行随机对照试验和队列研究,以澄清电子烟的安全性和口腔癌风险.
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