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Updated: May 22, 2025

A Syngeneic Pancreatic Cancer Mouse Model to Study the Effects of Irreversible Electroporation
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不可逆的电穿孔结合抗编程细胞死亡蛋白1疗法促进瘤抗原特异性CD8+T细胞反应

Yang-Yang Ma1, Xiao-Hua Wang1, Jian-Ying Zeng1

  • 1Central Laboratory, Guangzhou Fuda Cancer Hospital, Guangzhou 510665, Guangdong Province, China.

World journal of gastrointestinal oncology
|March 17, 2025
PubMed
概括

与抗编程细胞死亡蛋白1 (PD-1) 治疗相结合的不可逆向电穿孔 (IRE) 通过增加T细胞透和减少胰腺癌模型中的瘤体积,显著提高了抗瘤免疫力.

关键词:
抗癌免疫力 抗癌免疫力在 CD8+ T 细胞中.不可逆的电穿孔是不可逆的胰腺癌是一种胰腺癌.编程细胞死亡蛋白1封锁

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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