一个共享的基因但不同的动态调节了密切相关的物种中的模仿多态
Sofia I Sheikh1, Meredith M Doellman1,2, Nicholas W VanKuren1
1Department of Ecology & Evolution, The University of Chicago.
bioRxiv : the preprint server for biology
|March 17, 2025
概括
双性 (dsx) 基因控制 Papilio 蝶中的女性模仿. 尽管共享DSX使用,但不同的下游基因表达是密切相关物种的模仿进化的基础.
科学领域:
- 进化遗传学的进化遗传学
- 发育生物学是发展生物学.
- 动物颜色动物的颜色.
背景情况:
- 性限制的多态性,如雌性蝶模仿性,是常见的和适应性的,但它们的遗传基础是不太了解的.
- 帕皮里奥蝶表现出女性限定的模仿多态性,具有明显的模仿和非模仿的翅膀图案.
- 双性 (dsx) 基因与控制这些替代女性颜色模式有关.
研究的目的:
- 调查Papilio蝶中女性限定模仿多态性的分子和发育遗传基础.
- 确定双性 (dsx) 在控制性变态和模仿性方面的作用.
- 识别下游基因并比较基因机制,以模仿进化跨物种的基础.
主要方法:
- 进行RNA测序 (RNA-seq),对Papilio lowii雌性进行测序.
- 在几种Papilio物种中,dsx基因表达被实验性地操纵 (敲击).
- 基因表达数据比较了P. lowii和以前研究的P. alphenor.之间的数据.
主要成果:
- 抑制女性的DSX表达导致了类似男性的颜色模式,证实了DSX在性二重形和多重形的作用.
- dsx的等位基因在P. lowii和P. alphenor的模仿雌性中表现出独特的时空表达模式.
- 虽然某些翅膀模式基因在两种物种中都表达不同,但它们的时间表达模式显著不同.
结论:
- 双性 (dsx) 基因是Papilio蝶模仿多态性的关键调节者.
- 尽管dsx的作用得到保护,但驱动模仿进化的下游遗传路径在密切相关的物种之间是不同的.
- 这突出了共同的表型特征背后的不同进化机制.
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