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三糖糖体质指数与阻塞性睡眠呼吸暂停风险之间的关联的横截面研究

Li Gong¹, Ming Su², Jing-Han Xu³

¹Department of Diabetes, Shenzhen Bao'an Chinese Medicine Hospital Guangzhou University of Chinese Medicine, Shenzhen 518100, Guangdong Province, China.

World journal of diabetes

|March 17, 2025

概括

较高的甘油三糖-体质指数 (TyG-BMI),即胰岛素抵抗的指标,与阻塞性睡眠呼吸暂停 (OSA) 的患病率增加有关. 管理胰岛素抵抗可能有助于降低OSA风险.

科学领域:

代谢健康代谢健康
睡眠医学睡眠医学
心血管疾病风险因素心血管疾病风险因素

背景情况:

三糖糖-体质指数 (TyG-BMI) 是一种新型的胰岛素抵抗 (IR) 指标.
阻塞性睡眠呼吸暂停 (OSA) 是一种普遍存在的睡眠障碍,对健康有重大影响.
TyG-BMI和OSA之间的关联以前没有被探索过.

研究的目的:

调查TyG-BMI与美国大量成年人群中OSA发生的关系.
为了确定提升的TyG-BMI是否是发展OSA的风险因素.

主要方法:

一项使用国家健康和营养检查调查数据 (2005-2018) 的横截面研究.
TyG-BMI是使用甘油三,禁食血糖和BMI计算的.
限制立方线和考克斯回归分析了这种关联,进行了灵敏度和子组分析.

主要成果:

总共分析了16794名参与者.
经过对共变量进行调整后,较高的TyG-BMI与增加的OSA患病率显著相关 (OR:1.28;95% CI:1.17,1.40;P <0.001).
这种关联因年龄,性别,吸烟状况,婚姻状况,高血压和肥胖而有所缓和;在糖尿病患者中没有发现强烈的相关性.

结论:

提升的TyG-BMI与患上OSA的可能性更高有关.
TyG-BMI 作为一个潜在的OSA风险指标.
根据TyG-BMI的指标,管理胰岛素耐药性可能是减轻OSA风险的策略.

关键词:

一个横截面的截面.胰岛素耐药性胰岛素耐药性是一种国家健康和营养检查调查调查.阻塞性睡眠呼吸暂停症是什么三糖糖体质量指数-三糖糖体质量指数

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