内镜全厚切除:对于局部完全切除小直肠神经内分泌瘤的最终解决方案
Xiao-Long Zhang1, Yang-Yang Jiang2, Ying-Ying Chang2
1Digestive Endoscopy Center, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
World journal of gastroenterology
|March 17, 2025
概括
内镜全厚切除 (EFTR) 与内镜亚粘膜切除 (ESD) 相比,为小直肠神经内分泌瘤 (R-NENs) 提供更高的完整切除率. 这项研究突出了EFTR的重点.
科学领域:
- 胃肠病学和内镜检查
- 手术瘤学手术瘤学
- 胃肠道病理 胃肠道病理
背景情况:
- 直肠神经内分泌瘤 (R-NENs) 在使用当前内镜技术进行完全切除 (CR) 时存在挑战.
- 内镜全厚切除 (EFTR) 对于膜下瘤是有效的,但对于R-NENs没有充分利用.
- 实现100%的CR,特别是在垂直上,仍然是R-NEN治疗的目标.
研究的目的:
- 评估EFTR用于R-NEN切除的安全性和有效性.
- 在R-NEN治疗中,将EFTR结果与内镜下膜剖析 (ESD) 进行比较.
主要方法:
- 160名病理确诊R-NENs患者的回顾性队列研究.
- 28名接受EFTR治疗的患者和132名接受ESD治疗的患者之间的比较.
- 评估CR速率,块切除,操作时间,并发症和入侵深度.
主要成果:
- 对于1厘米和1-2厘米以下的R-NEN,EFTR实现了100%的CR率,明显高于ESD (分别为67.0%和50.0%).
- 所有接受EFTR治疗的患者都实现了块切除和成功的R-NEN切除.
- 在操作时间,成本和不良事件方面,EFTR的安全性和有效性与ESD相比较,住院时间略长.
结论:
- 与ESD相比,EFTR在切除小R-NEN方面表现优越.
- EFTR是一种安全有效的内镜技术,用于R-NEN治疗,特别是实现完全切除.
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