结构性种族主义和乳腺癌阶段在南佛罗里达州多数少数群体中呈现:一项回顾性研究
Alexandra E Hernandez1, Maya Lubarsky2, Ashly C Westrick3
1Division of Surgical Oncology, University of Miami Department of Surgery, Miami, FL, USA.
Lancet regional health. Americas
|March 17, 2025
概括
住宅隔离与晚期乳腺癌呈现有关. 以极端度指数 (ICE) 衡量的经济和种族隔离,在诊断时显著增加了晚期疾病的几率.
科学领域:
- 公共卫生 公共卫生
- 健康差距 研究 研究 研究 研究
- 在瘤学瘤学.
背景情况:
- 住宅隔离 (经济,种族,民族) 是健康的关键社会决定因素.
- 分离有助于乳腺癌结局的显著差异.
- 了解这些差异对于有针对性的干预至关重要.
研究的目的:
- 检查经济和种族/民族居住隔离与乳腺癌在呈现阶段之间的关联.
- 使用极端度指数 (ICE) 来量化隔离.
- 为了确定与晚期疾病相关的特定隔离模式.
主要方法:
- 在两个机构对4898名乳腺癌患者 (2005-2017年) 的回顾性研究.
- 使用美国社区调查数据 (2009-2013) 来计算五个ICE变量.
- 采用多级物流回归来分析隔离与疾病阶段之间的关联.
主要成果:
- 在经济上最边缘化的社区的患者患病后期呈现的几率增加了 (ORQ1: 1.38).
- 居住在大多数非西班牙裔黑人 (NHB) 或西班牙裔社区也与晚期疾病的更高几率相关.
- 综合NHB/经济和西班牙裔/经济隔离显示,晚期诊断的几率显著增加 (ORQ1:分别为1.64和1.60).
结论:
- 这项研究是首次将乳腺癌在呈现时的阶段与ICE联系起来.
- 研究结果表明,结构性种族主义显著影响了诊断时的疾病阶段.
- 干预措施必须解决社会和环境背景,以减少癌症差异.
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