儿童骨科患者静脉血栓栓塞的描述性流行病学:一项全国性的多中心研究
Hillary Brenda Nguyen1,2, Ryan M Sanborn2, Danielle Cook2
1Harvard Medical School, Boston, Massachusetts.
JB & JS open access
|March 17, 2025
概括
儿科骨科患者的静脉血栓栓塞 (VTE) 发病率高于其他儿科患者. 识别有风险的儿童和实施VTE预防方案对于预防并发症和死亡率至关重要.
科学领域:
- 儿科整形外科 儿科整形外科
- 血液学 血液学 血液学
- 血管医学 血管医学
背景情况:
- 在哪些儿科骨科患者需要静脉血栓塞栓症 (VTE) 预防方面缺乏共识.
- 进行了一项多中心综述,以探索儿科整形外科的VTE发病率和流行病学.
研究的目的:
- 确定和比较儿科骨科患者 (POPs) 与儿科非骨科患者 (PNOPs) 的VTE发病率.
- 分析人口统计,风险因素,预防,治疗和VTE在POP中的结果.
主要方法:
- 2014-2017年美国13个儿科中心的VTE发病率的多中心综述.
- 在住院和门诊环境中,POPs和PNOPs (0-18岁) 之间的VTE率的比较.
- 对POP VTE病例的描述性统计分析,包括人口统计,风险因素和预防使用.
主要成果:
- 整体VTE发生率为PNOPs的2.1/10,000,POPs的8.0/10,000.
- 常见的POP VTE风险因素包括骨科手术,细菌病,中央静脉导管和创伤.
- 34%的POP VTE病例接受了预防,97%接受了抗凝药治疗;2%的病例导致死亡.
结论:
- 儿科骨科患者的VTE发病率可能高于其他儿科组.
- 尽管采取了预防措施,但仍有很大一部分儿科VTE病例发生,这凸显了改善预防策略的必要性.
- 识别高风险的儿科骨科患者和建立最佳实践VTE预防方案对于降低发病率和死亡率至关重要.
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