探索患者结果的性别差异:爱尔兰心血管二次预防计划Heartwatch的二次分析
Ivana Keenan1, Fintan Stanley1, Robyn Homeniuk2
1Irish College of GPs, 4-5, Lincoln Pl, Dublin, D02 XR68, Ireland.
概括
爱尔兰Heartwatch计划的女性患者表现出比男性更糟糕的心血管结果和更高的风险概况. 这凸显了有针对性的干预措施的必要性,以改善女性的二次心血管疾病预防.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在过去二十年中,在心血管疾病 (CVD) 诊断,治疗和风险管理方面,已经注意到基于性别的差异.
- 爱尔兰的Heartwatch计划提供二次心血管预防服务.
研究的目的:
- 调查和比较爱尔兰二级心血管预防计划Heartwatch的男性和女性患者之间的心血管结果.
主要方法:
- 一项回顾性观察性研究分析了来自Heartwatch数据库 (2003-2017) 的匿名数据.
- 在基线和4年随访期间评估心血管风险因素.
- 采用了8点的综合风险评分 (CCare评分) 和概括估计方程进行分析.
主要成果:
- 包括8893名患者 (77%是男性);女性的风险概况较高,并且在血压和体力活动等关键因素上更频繁地偏离目标.
- 女性接受阿司匹林和ACE抑制剂的可能性较低,但更有可能被处方为AT2抑制剂,通道阻断剂和利尿剂.
- 在基线和4年随访后,在男性和女性之间观察到持续的CCare分数差距.
结论:
- 心脏观察计划改善了患者护理,但女性患者的表现始终不佳.
- 进一步的研究是必不可少的,以确保公平有效的二次预防爱尔兰妇女心血管疾病.
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