乙烯基cyclopropanes作为三碳synthons在催化循环添加物:反应开发,机械研究,新的灵感,和合成应用

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Updated: May 22, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

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Pan Zhang1, Zhi-Xiang Yu1

  • 1Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China.

Accounts of chemical research
|March 17, 2025
PubMed
概括

研究人员开发了新的过渡金属催化循环添加剂,使用乙烯基cyclopropanes (VCPs) 作为三碳 synthons. 这些反应有效地构建复杂的化环系统,包括具有挑战性的七个环和桥头四元中心.

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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