青春期女孩的硬质素和骨质:运动员和非运动员之间的不同关联
Jaak Jürimäe1, Liina Remmel2, Anna-Liisa Tamm3
1Institute of Sport Sciences and Physiotherapy, Faculty of Medicine, University of Tartu, Tartu, Estonia - jaak.jurimae@ut.ee.
The Journal of sports medicine and physical fitness
|March 17, 2025
概括
与未经训练的同龄人相比,年轻的节奏体操运动员表现出更高的硬质素水平,这是骨形成的负面调节剂. 斯克莱洛斯在体操运动员和早期青春期的对照中显示出与骨质的明显关联.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 运动医学运动医学
- 骨生物学 骨生物学
背景情况:
- 节奏体操运动员 (RG) 从小就接受了强烈的训练,通常身体脂肪很低,但骨参数比未经训练的对照者 (UC) 高.
- 在青春期骨发育中,硬质素和前脂质细胞因子-1 (Pref-1),骨形成抑制剂的作用尚未完全理解.
- 研究这些因素对于了解年轻运动员的骨健康至关重要.
研究的目的:
- 为了比较年轻的节奏体操运动员和未经训练的对照者之间的血硬质素和Pref-1水平.
- 为了检查这些两组中斯克莱洛斯,Pref-1和骨质之间的关系.
- 阐明这些骨调节剂在运动员早期青春期的作用.
主要方法:
- 这项研究包括32名节奏体操运动员 (RG) 和32名未经训练的对照人 (UC),年龄在10-12岁之间.
- 用双能X射线吸收计来评估骨质和身体组成.
- 从禁食血液样本中测量了硬质素和Pref-1的血度.
主要成果:
- 与UC相比,RG中的血硬质素显著高于RG (24.2±8.8与14.7±10.0 pmol/L).
- 在各组之间,Pref-1水平没有差异.
- 在RG中,硬质与腰椎和大腿部骨矿物质含量呈正相关,而在UC中,它显示了相反的关联. 在调整了混因素后,这些相关性在RG中仍然显著.
结论:
- 与未经训练的同龄人相比,早期青春期节奏体操运动员的血硬质素水平较高.
- 斯克莱洛斯在节奏体操运动员和未经训练的对照人群中表现出与骨质的差异性关联.
- 这些发现表明,在年轻的女性运动员中,骨调节机制是独特的.
相关概念视频
01:29Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
01:17Hormones and Bone Tissue
2.5K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.5K
01:27Signs of Puberty
196
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
196
01:09Changes in the Appendicular Skeleton with Age
1.8K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
1.8K
01:31Osteoclasts in Bone Remodeling
2.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
2.8K
01:02What is the Skeletal System?
52.1K
Overview
52.1K