虚弱和垂体外科手术:一个系统的审查
Mendel Castle-Kirszbaum1,2, Ann McCormack3,4, Christopher Ovenden5,6
1Department of Neurosurgery, Monash Health, 246 Clayton Road, Clayton VIC 3168, Melbourne, Australia. mdck.journal@gmail.com.
Pituitary
|March 17, 2025
概括
虚弱增加了医疗并发症和死亡率,在经历过脑下垂体外科手术的患者. 然而,手术成功率没有受到影响,突出显示虚弱是风险预测因素,而不是拒绝手术的理由.
科学领域:
- 神经外科 神经外科
- 老年医学 老年医学
- 外科手术的结果
背景情况:
- 虚弱,一种生理脆弱的状态,增加了神经外科病人的不良外科期结果的风险.
- 虚弱对脑下垂体外科手术结果和并发症的具体影响仍然在很大程度上未被描述.
研究的目的:
- 系统地审查和综合现有的文学关于虚弱和结果之间的关联在经过跨状垂体手术的患者.
主要方法:
- 按照PRISMA指南进行了一次系统的文献审查.
- 包括使用经过验证的虚弱度指标来评估海马体外科手术患者的结果的研究.
主要成果:
- 该审查包括13项涉及124,989名患者的研究,并注意到脆弱性评估和定义的异质性.
- 脆弱的患者经历了明显更高的医学并发症率,更长的住院时间,增加的成本,更高的再入院率和更高的死亡率.
- 手术结果,包括生化缓解,视力恢复和生活质量,没有受到脆弱的显著影响.
结论:
- 虚弱是脑垂体手术中术后风险的重要指标,影响少数患者.
- 脆弱性评估应指导外科手术期间的风险减轻策略,而不是作为手术的禁忌.
- 积极管理脆弱性可以改善经过跨状垂体手术的患者的整体结果.
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