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Updated: May 22, 2025

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity
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降低PLK1调节通过抑制ERK1/2通路来减轻ET-1诱导的心肌细胞缩

Jie Ding1, Anqi Yang1, Liping Zhou1

  • 1Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, China.

Journal of cardiovascular translational research
|March 17, 2025
PubMed
概括

波罗样酶1 (PLK1) 驱动心肌细胞缩,这是心力衰竭发展的关键因素. 抑制PLK1减少心脏细胞扩大和标记物,为心脏病提供潜在的治疗策略.

关键词:
心肌细胞过度增生在ERK1/2中.输内甲林-1-1是什么PLK1 PLK1 的意思是这就是hiPSC-CMs.

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