在类风湿性关节炎中抑郁和焦虑的影响和患病率 - - 一项采用自我报告问卷的横截面研究
Cătălina-Elena Ionescu1,2, Claudiu C Popescu1,2, Cătălin Codreanu1,2
1Rheumatology Department, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Journal of clinical medicine
|March 17, 2025
概括
抑郁症和焦虑症在风湿性关节炎 (RA) 患者中很常见,与疼痛和残疾增加有关. 早期查对于更好地管理RA及其心理并发症至关重要.
科学领域:
- 类风湿病学 类风湿病学
- 精神病学是一个精神病学.
- 临床医学 临床医学
背景情况:
- 类风湿性关节炎 (RA) 是一种慢性自身免疫性疾病,影响关节.
- 在RA患者中经常观察到抑郁症和焦虑症等精神健康并发症.
- 不充分报告这些情况可能导致诊断延迟和不理想的患者护理.
研究的目的:
- 在现实世界风湿性关节炎患者队列中选抑郁和焦虑.
- 调查RA表型特征,疾病活动和心理健康结果之间的关联.
- 确定RA患者中抑郁症和焦虑症的患病率.
主要方法:
- 一项在三级风湿病医院进行的横截面研究.
- 在为期一个月的疾病随访期间,包括209名类风湿性关节炎患者.
- 使用患者健康问卷-9 (PHQ9) 进行抑郁和医院焦虑和抑郁量表 (HADS) 进行焦虑查.
主要成果:
- 可能的抑郁症患病率为34.4% (PHQ9) 和14.8% (HADS-D);可能的焦虑症患病率为32.5% (HADS-A).
- 对抑郁症或焦虑症呈阳性查的患者的疾病活动得分 (DAS28),关节计数和功能障碍显著增加.
- 焦虑在女性中更为普遍,她们还报告了较高的柔软关节数量和功能阶段.
结论:
- 抑郁症和焦虑症非常普遍,并且在类风湿性关节炎患者中经常被低估.
- 这些心理健康状况与 RA 疼痛增加,功能障碍和疾病活性显著相关.
- 抑郁症和焦虑症的查应该是常规RA患者护理的组成部分.
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