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Updated: May 21, 2025

An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity
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An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity

Published on: October 8, 2018

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在人类肝细胞癌细胞中,TRIM21调节了支持生存的非编码RNAvtRNA1-1的稳定性

EunBin Kong1, Norbert Polacek1

  • 1Department for Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Bern, Switzerland.

PLoS genetics
|March 17, 2025
PubMed
概括

新的研究确定了TRIM21和TRIM25蛋白质,可以稳定肝癌细胞中的密室RNA 1-1 (vtRNA1-1). 这一发现为开发抗癌疗法提供了潜在的新策略.

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