基于耳朵和指尖的光电显微传感器的评估,用于测量心脏虚脉相关心率变化参数
Ankit Parikh1,2, Gwyn Lewis3, Hamid GholamHosseini4
1School of Clinical Sciences, Auckland University of Technology, Auckland 0627, New Zealand.
Sensors (Basel, Switzerland)
|March 17, 2025
概括
一个指尖传感器准确地测量了心率变化 (HRV) 参数,用于便携式迷走神经刺激. 一个拉伸传感器也显示出很好的精度检测呼吸,使得在家中使用呼吸门的taVNS系统.
科学领域:
- 生物医学工程 生物医学工程
- 神经科学是一个神经科学.
- 生理学 生理学 生理学
背景情况:
- 目前的呼吸门通透皮肤耳道迷走神经刺激 (taVNS) 研究依赖于非便携式实验室设备.
- 这限制了对受控环境的研究,并带来了后勤挑战.
- 开发便携式传感器系统对于在家进行方便的taVNS研究至关重要.
研究的目的:
- 评估耳朵内和指尖光电显微镜 (PPG) 传感器用于测量心率变化 (HRV) 参数的准确性.
- 为了评估拉伸传感器在检测呼吸道门的呼气时的准确性.
- 确定这些便携式传感器是否适合开发家庭使用的taVNS系统.
主要方法:
- 30名健康参与者同时使用原型PPG传感器和黄金标准心电图 (ECG) 记录心跳间隔.
- 在正常呼吸和深慢呼吸 (DSB) 期间进行记录.
- 使用布兰德-阿尔特曼分析和类内相关系数 (ICC) 来评估一致性和一致性;使用真正率 (TPR),假正率 (FPR) 和假负率 (FNR) 来评估伸展传感器的准确性.
主要成果:
- 指尖PPG传感器在两个呼吸条件下测量RMSSD (一个关键HRV参数) 显示了可接受的协议.
- 在正常呼吸过程中,指尖传感器与HF-HRV (另一个HRV参数) 达成可接受的协议.
- 伸展传感器表现出可接受的准确性,平均TPR在正常呼吸时为85%,在DSB时为95%.
结论:
- 传感器之间的高相关性并不保证测量生理参数的一致性.
- 基于指尖的PPG传感器和拉伸传感器显示可接受的准确性,可集成到便携式呼吸门taVNS系统中.
- 这些发现支持开发便携式taVNS系统,用于方便的家庭研究和潜在的治疗应用.
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