血压不同妊娠阶段的表型变化和相关的怀孕风险
Lushu Zuo1, Yiwen Fang1, Linjie Li1
1Department of Cardiology, Tianjin Medical University General Hospital.
American journal of hypertension
|March 17, 2025
概括
妊娠高血压疾病 (HDP) 的风险因血压表型和妊娠阶段而异. 门诊BP监测对于识别风险和优化结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 心脏病学 心脏病学
- 周围生理学 周围生理学
背景情况:
- 妊娠高血压障碍 (HDP) 增加了不良妊娠结果 (APO).
- 血压 (BP) 现型 (面具高血压,白袍高血压,持续高血压,正常血压) 通过办公室BP (OBP) 和门诊BP (ABP) 监测来确定.
- 在整个妊娠期内,BP表型的患病率及其与APO的相关性尚未得到充分了解.
研究的目的:
- 调查不同妊娠年龄的BP表型的比例.
- 为了确定BP表型和APO在整个孕期之间的关联.
主要方法:
- 对967名患有HDP风险或诊断的妇女进行了回顾性研究.
- 在各种妊娠阶段 (0-19+6,20+0-29+6,30+0-32+6,33+0-35+6,≥36+0GW) 进行的OBP和ABP测量.
- APO定义为母体和胎儿结合后果.
主要成果:
- 在20+0-29+6GW的血压监测显示了最低的血压和最高的血压常见率.
- 根据ABP定义的高血压与APO的关联比OBP更强.
- 持续高血压 (SH) 的APO风险最高,在20+0GW之后随着妊娠的推进而下降.
- 蒙面高血压 (MH) 与30+0-32+6 GW之间的APO有关.
- 白袍高血压 (WCH) 与胎儿的结果没有关联.
结论:
- 根据妊娠阶段,BP表型与APO的关联有很大差异.
- 早期检测到的SH具有最高的风险;WCH通常对胎儿结果是良性的.
- ABP监测对于BP表型化至关重要,需要为定制干预措施制定妊娠阶段特定的门.
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