发展中的视觉系统:在通往自闭症的道路上构建的基石
1Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Developmental cognitive neuroscience
|March 17, 2025
概括
在自闭症谱系障碍 (ASD) 中,视觉系统的早期发育显示了与遗传因素相关的非典型模式. 了解这些早期的视觉变化是解开ASD的关键.
科学领域:
- 神经发育障碍 神经发育障碍
- 自闭症谱系障碍 (ASD) 是一种
- 视觉系统开发 视觉系统开发
背景情况:
- 纵向神经成像显示了ASD早期儿童的异常视觉系统发育.
- 遗传因素与ASD视觉系统的改变有关,突出显示它是关键的神经表型.
- 视觉系统的发展对于理解自闭症患者从基因到行为的轨迹至关重要.
研究的目的:
- 审查当前关于ASD早期视觉系统发育的知识.
- 探索非典型视觉系统成熟在ASD的出现中的作用.
- 在涉及大脑,注意力和社会认知发展的发展级联中对发现进行上下文化.
主要方法:
- 纵向神经成像研究的综述.
- 整合了基因组分析,家庭研究和死后调查的发现.
- 发展级联模型的语境化.
主要成果:
- 有证据表明,在ASD中,早期生活中异常的视觉系统发育.
- 遗传因素有助于这些视觉系统变化.
- 非典型的视觉成熟可能会影响影响ASD的发展级联.
结论:
- 发展中的视觉系统在ASD是进一步研究的关键领域.
- 解决了解早期视觉发育的差距对于理解ASD至关重要.
- 未来的研究应该专注于早期大脑发育在ASD病因学中的作用.
相关概念视频
Autism Spectrum Disorder
77
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
77
Visual System
561
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
561
Vision
53.1K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
53.1K
What is a Sensory System?
93.1K
Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
93.1K
Anatomy of the Eyeball
6.7K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
6.7K
Piaget's Stage 1 of Cognitive Development
609
The sensorimotor stage, the initial phase of Jean Piaget's theory of cognitive development, spans the first two years of a child's life. During this period, infants actively engage with their surroundings, building cognitive awareness through direct interaction with the world. This interaction is primarily based on sensory perception and motor actions, allowing infants to gradually understand basic physical properties and predict how objects interact within their environment.
609


