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Updated: May 21, 2025

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
10:07

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Published on: January 27, 2013

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在片选中寻找选择性通道阻断剂:当大小很重要时

Maximiliano José Fallico1, Lucas Nicolás Alberca1, Nicolás Enrique2

  • 1Laboratory of Bioactive Compounds Research and Development (LIDeB), Faculty of Exact Sciences, National University of La Plata (UNLP), La Plata, Buenos Aires, Argentina.

Brain research
|March 17, 2025
PubMed
概括

机器学习模型通过准特定的通道来确定Dravet综合征的潜在候选药物. 虽然一些药物表现出NaV1.2阻断作用,但亚型选择性仍然是治疗这种严重的挑战.

关键词:
数据集大小 数据集大小德拉维特综合征是什么?德拉维特综合征是什么是一种病.在 NaV1.1 中使用.NaV1.2 和 NaV1.2 是不同的.通道阻断剂是一种通道阻断剂.

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